Hubungan Antara Gejala Klinis dan Tatalaksana Terapi Stroke dengan Outcome Stroke Disertai COVID-19 di Rumah Sakit Umum Daerah Jawa Barat Tahun 2021

Hutagaol, Oskar Yuda Daud Marcello (2022) Hubungan Antara Gejala Klinis dan Tatalaksana Terapi Stroke dengan Outcome Stroke Disertai COVID-19 di Rumah Sakit Umum Daerah Jawa Barat Tahun 2021. S1 thesis, Universitas Kristen Indonesia.

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Abstract

Pandemi COVID-19 merupakan tantangan berbagai negara di seluruh dunia. Jumlah kasus COVID-19 di Indonesia hingga tanggal 31 Juli 2021 berjumlah 3,37 juta kasus terkonfirmasi positif, 2,73 juta sembuh, dan sebanyak 92.311 meninggal dunia. Virus ini dapat menyebabkan gangguan pada sistem pembuluh darah dan sistem hemostasis-koagulasi yang dapat meningkatkan risiko terjadinya stroke. Beberapa penelitian telah melaporkan stroke disertai COVID-19 namun penelitian tentang hubungan antara gejala klinis, tatalaksana terapi dengan outcome stroke disertai COVID-19 di rumah sakit umum daerah Jawa Barat belum pernah dilakukan sehingga perlu diteliti. Mengetahui hubungan antara gejala klinis, tatalaksana dengan outcome penderita stroke disertai COVID-19 di rumah sakit umum daerah Jawa Barat tahun 2021. Merupakan penelitian analitik. Menggunakan data rekam medik pasien stroke disertai COVID-19 di rumah sakit umum daerah Jawa Barat periode Januari-Desember tahun 2021. Kriteria inklusi pasien menderita stroke iskemik dan hemoragik disertai COVID-19 dan hasil PCR positif, kriteria eksklusi pasien sudah pernah stroke sebelum COVID-19. Data yang didapatkan di uji menggunakan uji korelasi Spearman. Jenis kelamin laki-laki (51%), usia terbanyak 46-65 (51,7%) gejala klinis COVID-19 berat (91,8%) dan gejala stroke hemiparesis sinistra (36,7%), antivirus terbanyak favipiravir (63,3%), obat stroke terbanyak citicolin (93,8%) aspilet (43%) dan bantuan napas terbanyak non-rebreathing mask (65,3%), outcome terbanyak meninggal (46,9%), Uji statistik Spearman didapatkan hubungan tidak bermakna antara gejala klinis COVID-19 dengan outcome (p>0,05) dan jenis alat bantuan napas dengan outcome memiliki hubungan yang tidak bermakna (p>0,05). Sedangkan pada uji statistik antara tatalaksana terapi dengan outcome terdapat hubungan yang bermakna (p<0,05).Hubungan antara derajat gejala klinis dan jenis bantuan napas dengan outcome dirumah sakit umum daerah Jawa Barat memiliki hubungan yang bermakna antara ketiga variable tersebut./ The COVID-19 pandemic is a challenge for various countries around the world. The number of COVID-19 cases in Indonesia as of July 31, 2021, was 3.37 million positive confirmed cases, 2.73 million recovered, and 92,311 died. This virus can cause disturbances in the blood vessel system and the hemostasis-coagulation system which can increase the risk of stroke. Several studies have reported stroke accompanied by COVID-19 but research on the relationship between clinical symptoms, therapeutic management and outcomes of stroke with COVID-19 in West Java general hospitals has never been carried out so it needs to be investigated. To determine the relationship between clinical symptoms, treatment with the outcome of stroke patients with COVID-19 in a West Java regional general hospital in 2021. An analytical study. Using medical record data of stroke patients with COVID-19 at public hospitals in West Java for the period January-December 2021. Inclusion criteria for patients suffering from ischemic and hemorrhagic stroke accompanied by COVID-19 and positive PCR results, exclusion criteria for patients who had had a stroke before COVID-19 19. The data obtained were tested using the Spearman correlation test. Male gender (51%), the most age 46-65 (51.7%) clinical symptoms of severe COVID-19 (91.8%) and left hemiparesis stroke symptoms (36.7%), the most antiviral favipiravir (63.3%), the most stroke drug was citicolin (93,8%) aspirin (43%) and the most respiratory assistance was non-rebreathing mask (65.3%), the most outcome was death (46.9%), Spearman statistical test found a correlation There was no significant relationship between clinical symptoms of COVID-19 and outcome (p>0.05) and the type of breathing apparatus with outcome had a non-significant relationship (p>0.05). Meanwhile, in the statistical test between therapeutic management and outcome, there was a significant relationship (p<0.05). The relationship between the degree of clinical symptoms and the type of respiratory support with the outcome of a general hospital in West Java has a significant relationship between the three variables

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