Evaluasi Pemberian Obat pada Pasien Chronic Kidney Disease tentang Adanya Drug Related Problems di Rumah Sakit Umum UKI Periode Tahun 2016-2018

Handoko, Henry (2018) Evaluasi Pemberian Obat pada Pasien Chronic Kidney Disease tentang Adanya Drug Related Problems di Rumah Sakit Umum UKI Periode Tahun 2016-2018. S1 thesis, Universitas Kristen Indonesia.

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Abstract

Drug related problems (DRPs) menjadi masalah umum pada pasien chronic kidney disease (CKD) terutama akibat obat yang diberikan terlalu banyak dan bisa mengalami interaksi obat. Penelitian ini menggunakan metode content analysis dengan pendekatan retrospektif observasional Sampelnya adalah semua kasus CKD di RSU UKI periode tahun 2016-2018. Dilakukan analisa karakteristik pasien, karakteristik farmakoterapi dan interaksi obat. Hasil penelitian didapatkan pasien CKD sebanyak 73 pasien dan didapatkan wanita dan rentang umur 55-64 tahun menjadi yang terbanyak. Farmakoterapi yang diberikan kepada pasien CKD sebanyak 549 obat dan rentang pemberian 5-10 obat per pasien menjadi yang terbanyak. Terjadi Interaksi obat terjadi pada 63 pasien (86,3 %) dan 197 interaksi obat (59,1%) berada pada tingkat keparahan yang harus dipantau.Pada uji pearson correlation didapatkan nilai sebesar 0,717 yang menunjukkan hubungan yang signifikan antara jumlah pemberian obat dengan jumlah interaksi obat. Kata Kunci: DRPs, CKD, interaksi obat. / Drug related problems (DRPs) are a common problem in patients with chronic kidney disease (CKD) mainly due to drugs that are given too much and can experience drug interactions. This study used the content analysis method with an observational retrospective approach. The sample consisted of all CKD cases at the UKI General Hospital for the period 2016-2018. Analyzed patient characteristics, pharmacotherapy characteristics and drug interactions. The results of the study showed that 73 patients with CKD and women were found and the age range of 55-64 years was the most. Pharmacotherapy given to CKD patients is 549 drugs and the range of administration of 5-10 drugs per patient is the most. Occurrence drug interactions occurred in 63 patients (86.3%) and 197 drug interactions (59.1%) are at the level of severity that must be monitor closely. The Pearson correlation test obtained a value of 0.717 which showed a significant relationship between the amount of drug administration and the number of drug interactions. Keywords: DRPs, CKD, drug interactions

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