Gambaran Efektivitas Petidin dan Ondansetron pada Pasien Shivering karena Anestesi Spinal di RSU UKI Periode Januari - Juli Tahun 2023

Pakilaran, Arnold William (2023) Gambaran Efektivitas Petidin dan Ondansetron pada Pasien Shivering karena Anestesi Spinal di RSU UKI Periode Januari - Juli Tahun 2023. S1 thesis, Universitas Kristen Indonesia.

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Abstract

Teknik anestesi spinal merupakan teknik yang dilakukan dengan menyuntikkan dosis rendah anestesi lokal dan opioid ke ruang subarakhnoid pada L3-L4 dan L4-L5. Anestesi spinal biasanya digunakan dalam operasi pada segmen bawah abdomen, pelvis dan ekstremitas bawah. Menggigil merupakan komplikasi umum dari anestesi spinal, dengan angka kejadian mencapai 55% pada penelitian yang dilakukan di Irlandia pada tahun 2008. Menggigil menyebabkan peningkatan konsumsi oksigendan produksi karbon dioksida hingga tiga kali lipat. Petidine, sebagai agen farmakologi, telah lama digunakan sebagai pencegahan dan pengobatan menggigil selama operasi dan pascaoperasi dengan dosis yang disarankan yaitu dengan dosis 50 mg/g IV yaitu 30 – 60 menit sesudah operasiPetidin, berfungsi sebagai agonis (aktivator) reseptor opioid κ dan bekerja dengan mengikat dan merangsang reseptor κ di tubuhOndansetron adalah antagonis 5-HT merupakan anti-emetik yang banyak digunakan selama kehamilan dan pembedahan Kata Kunci : Shivering,Petidin,Ondansetron,Efektivitas. / Spinal anesthesia technique is a technique performed by injecting low doses of local anesthesia and opioids into the subarachnoid space at L3-L4 and L4-L5. Spinal anesthesia is usually used in surgery on the lower segments of the abdomen, pelvis and lower extremities. Shivering is a common complication of spinal anesthesia, with an incidence rate of 55% in a study conducted in Ireland in 2008. Shivering leads to increased oxygen consumption and carbon dioxide hin production up to three times. Petidine, as a pharmacological agent, has long been used as a prevention and treatment of chills during surgery and postoperative with the recommended dose of 50 mg / g IV which is 30 – 60 minutes after surgeryPetidin, functions as an agonist (activator) of κ opioid receptors and works by binding and stimulating κ receptors in the bodyOndansetron is a 5-HT antagonist is an anti-emetic that is widely used during pregnancy and surgery Keywords : Shivering,Petidin,Ondansetron,Effectiveness

Item Type: Thesis (S1)
Contributors:
ContributionContributorsNIDN/NIDKEmail
Thesis advisorHutapea, Ratna EmeliaNIDN0308046807ratnaemelia2@gmail.com
Additional Information: Nomor Panggil : T.A 617.964 Pak g 2023
Subjects: MEDICINE > Surgery > Anesthesiology
Divisions: FAKULTAS KEDOKTERAN > Pendidikan Dokter
Depositing User: Users 4167 not found.
Date Deposited: 10 Jan 2024 04:44
Last Modified: 02 Feb 2024 02:01
URI: http://repository.uki.ac.id/id/eprint/13361

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