My Way to Correct The Complication of Nasal Injection

Harlim, Ago (2017) My Way to Correct The Complication of Nasal Injection. In: WCD 2017, 4-6 Mei 2017, Bengaluru.

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Abstract

Silicone injection has been used since 40 years ago and at that time, many problems occurred such as migration, inflammation, and granuloma. In 1992, FDA prohibited silicone injection for cosmetic use.1 In addition to injection silicone may be introduced into our body or skin through food intake and cosmetic. Silicone has been widely used in daily cosmetics. Nowadays, due to technology advances, topical drugs can pass through skin barrier and can be penetrated into the skin, which has become a great concern as it may induce granuloma formation. There are relatively very few studies have been done on silicone concentration in normal skin. A study conducted by A Harlim in 2018 found that normal skin contained silicone. The study was performed by taking skin samples from normal subjects and those with face-lift procedure and subsequently compared those samples using the same criteria with the control group, which included skin samples of subjects that had received silicone injection and the study found granuloma formation. The study found an average amount of silicone level of 44.07±75.86 μg/g in patients with normal skin; while in patients with granuloma, they found 38 times greater silicone level (1709.21±1851.72 μg/g).2

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