Profil Overweight dan Hubungan Obesitas dengan Hemoglobin, Leukosit, dan Neutrofil Mahasiswa FK UKI

Aurellita, Nindya (2023) Profil Overweight dan Hubungan Obesitas dengan Hemoglobin, Leukosit, dan Neutrofil Mahasiswa FK UKI. S1 thesis, Universitas Kristen Indonesia.

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Abstract

Kelebihan berat badan (overweight dan obesitas) menjadi salah satu ancaman bagi kesehatan masyarakat. World Health Organization (WHO) menyatakan khususnya obesitas sebagai penyakit kronis. Seseorang dengan status gizi lebih memiliki risiko mengalami anemia dibandingkan dengan status gizi normal karena meningkatnya kadar hepsidin di dalam tubuh dapat mengganggu absorbsi besi. Obesitas berhubungan dengan anemia pada orang dewasa dan dianggap sebagai faktor proinflamasi yang ditandai dengan adanya inflamasi sistemik kronis tingkat rendah Respons inflamasi sistemik kronis tingkat rendah pada obesitas dikaitkan dengan jumlah leukosit dan neutrofil yang tinggi. Penelitian ini bertujuan untuk mengetahui profil overweight dan hubungan obesitas dengan kadar hemoglobin, leukosit, dan neutrofil mahasiswa FK UKI angkatan 2019-2021. Metode penelitian yang digunakan adalah analitik korelasi dengan pendekatan cross sectional, yang diperoleh dari data primer melalui pengukuran Indeks Massa Tubuh dan pemeriksaan kadar hemoglobin, leukosit, dan neutrofil. Data yang didapatkan diolah menggunakan uji korelasi Spearman. Subjek penelitian ini berjumlah 60 orang (30 Overweight dan 30 obesitas) yang berasal dari mahasiswa FK UKI angkatan 2019-2021. Uji korelasi Spearman kelompok overweight menunjukkan korelasi dengan hemoglobin (r=-0.132, p=0.488), leukosit (r=0,210, p=0.265), dan neutrofil (r=0.260, p=0,164). Uji korelasi Spearman kelompok obesitas yang menunjukan korelasi dengan hemoglobin (r=-0.032, p=0.868), leukosit (r=0.241, p=0.199), dan neutrofil (r=0.157, p=0.406). Berdasarkan data yang ada maka dapat disimpulkan profil rerata IMT kelompok obesitas (24.18) kelompok overweight (31.78). Uji korelasi menunjukkan hubungan korelasi yang lemah (tidak signifikan) obesitas dengan kadar hemoglobin, leukosit, dan neutrofil mahasiswa kedokteran FK UKI angkatan 2019-2021. Kata Kunci: Overweight, obesitas, hemoglobin, leukosit, neutrofil. / Overweight (overweight and obesity) is a threat to public health. The World Health Organization (WHO) specifically states obesity as a chronic disease. Someone with more nutritional status has a risk of developing anemia compared to normal nutritional status because increased levels of hepcidin in the body can interfere with iron absorption. Obesity is associated with anemia in adults and is considered a proinflammatory factor characterized by the presence of low-grade chronic systemic inflammation. A low-grade chronic systemic inflammatory response in obesity is associated with high leukocyte and neutrophil counts. This study aims to determine the overweight profile and the relationship between obesity and hemoglobin, leukocyte, and neutrophil levels in UKI Faculty of Medicine students 2019-2021. The research method used was analytic correlation with a cross-sectional approach, which was obtained from primary data through measurements of body mass index and examination of hemoglobin, leukocyte and neutrophil levels. The data obtained was processed using the Spearman correlation test. The subjects of this study were 60 people (30 Overweight and 30 obese) who came from UKI FK students class 2019-2021. The Spearman correlation test for the overweight group showed a correlation with hemoglobin (r=-0.132, p=0.488), leukocytes (r=0.210, p=0.265), and neutrophils (r=0.260, p=0.164). Spearman correlation test for the obese group showed a correlation with hemoglobin (r=-0.032, p=0.868), leukocytes (r=0.241, p=0.199), and neutrophils (r=0.157, p=0.406). Based on the available data, it can be concluded that the average BMI profile for the obese group (24.18) for the overweight group (31.78). The correlation test showed a weak (not significant) correlation between obesity and hemoglobin, leukocyte, and neutrophil levels of UKI Faculty of Medicine students 2019-2021. Keywords : Overweight, obesity, hemoglobin, leukocytes, neutrophils

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