Effect of torbangun (Coleus amboinicus Lour) on blood pressure in women with hypercholesterolemia

Suryowati, Trini and Gultom, Moskwadina (2019) Effect of torbangun (Coleus amboinicus Lour) on blood pressure in women with hypercholesterolemia. Journal of Physics: Conference Series.

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Abstract

Torbangun is known for medicinal properties, as antihyperlipidemic, antihyperglicemic. We investigate the effect of a phenolic-rich Torbangun leaf aqueous extract on women with hypercholesterolemia. The first step of this study was analyzed bioactive compound of Torbangun aqueous extract. The next step was administered orally of Torbangun extract to control and women with hypercholesterolemia for 30 days, 30 subjects placed in two groups, viz, experimental (CC group) and placebo (PC group). The first group received one capsule of CC (contains 500 mg extract) while the second group received one capsule of the PC (comprised of 500 mg fillers) one times daily for both groups. Blood pressure (BP), body mass index (BMI) and total cholesterol (TC) were measured in the first and the end of the intervention. Data were analyzed by paired sample t-test with 95% significance level. The results show that there was a significant decrease in TC on day 30, compared to control (PC group), and not significant for BMI. In CC group, the capsules significant reduction in TC levels (p=0.000). Studies clearly demonstrated that Torbangun extract possesses antihypercholesterolemic activity in women with hypercholesterolemia. Based on the results of this study Torbangun extract reduced BMI but has not antihypertensive property.

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