OPTIMASI ISOLASI SEL PUNCA DARI JARINGAN LEMAK MANUSIA DAN IMMUNOPHENOTYPING

Abbas, Rilianawati and Rofaani, Elrade and Harlim, Ago (2017) OPTIMASI ISOLASI SEL PUNCA DARI JARINGAN LEMAK MANUSIA DAN IMMUNOPHENOTYPING. In: Prosiding : Innovation of Bioeconomics on Agroindustrial and Biotechnology Programme. BPPT Press, Serpong, pp. 198-203. ISBN 975 602 410 097 1

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Abstract

In the past few decades, attention and research in the field of stem cell are progressing very rapidly. Hospitals in Indonesia have been using stem cells as an alternative to cure some illnesses like diabetes, heart disease, fractures and joints, dental implants, and asthma. Currently, adult stem cells can be obtained not only from the spinal cord and peripheral vessels, but also from fat tissues of the human body, where it can be isolated as adherent stem cells (mesenchymal stem cells). Human adipose tissue is a great source of mesenchymal stem cells. Adipose-derived mesenchymal stem cells (AD-MSCs) are easily isolated, can differentiate into multi-lineage cells and have various clinical application. Consideration of fat tissue as the source of mesenchymal stem cells (MSCs) for autologous tissue engineering is because they are readily available in abundant quantities through minimal invasive procedures, as well as easily cultured and propagated. Besides, the fat tissue is a type of adult stem cells (ASCs) that capable of metamorphosis / transdifferentiation into various strains due to the nature of high plasticity. Therefore it is possible to proliferate and differentiate into the desired direction of the network. Therefore, the aim of this study is to support the government in providing a stem cell production technology that can be used for alternative treatment for diseases that are difficult to cure with chemical treatments such as cancer and diabetes.

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