A MINI REVIEW OF INDONESIAN MEDICINAL PLANTS FOR VULVOVAGINAL CANDIDIASIS

Karo, Marni Br and Tambaip, Titus and Hatta, Mochammad and Simanjuntak, Tigor Peniel and Irmawaty, Lenny and Rina, Tetty and Kamelia, Emma and Rahmawati, Fri and Bintang, Maria (2017) A MINI REVIEW OF INDONESIAN MEDICINAL PLANTS FOR VULVOVAGINAL CANDIDIASIS. Rasayan Journal Chemistry, 10 (4). pp. 1280-1288. ISSN 0976 0083

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Official URL: http://rasayanjournal.co.in/

Abstract

Vulvovaginal candidiasis (VVC) is the second normal of vaginal mucosal infection after bacterial that influencing right around 70%-75% of women once in a lifetime. Azoles antibiotics are used in treatment for VVC but limited because cause drug resistance in patients. Therefore, today need for new antifungal agents for Candida albicans infection that safe and without side effect. This article reviews Indonesian medicinal plants related to the antifungal activity and mechanisms of action against C. albicans. The searches for this review were conducted via the databases PubMed, Google Scholar, online Science Direct, Science and Technology Index. The document relevant analyzed and included in the study. Almost 34 medicinal plants used for anti-Candida in Indonesia were reported. About 5.88% and 94.12% of Indonesian medicinal plants were significant and weak as an anti-Candida activity, respectively. The plants with the greatest anti-Candida activity were Curcuma xanthorrhiza and Syzygium aromaticum. The anti-Candida action involved disruption of hyphae production, membrane permeabilization, cell wall, biofilm formation, envelope, and filament formation. These results contribute to the drug discovering of the anti-Candida from Indonesian medicinal plants.

Item Type: Article
Subjects: MEDICINE > Botanic, Thomsonian, and eclectic medicine
Depositing User: Edi Wibowo
Date Deposited: 18 May 2020 06:35
Last Modified: 04 Sep 2020 04:47
URI: http://repository.uki.ac.id/id/eprint/1708

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