Sindrom Nefrotik Resisten Steroid

Manalu, Erida (2019) Sindrom Nefrotik Resisten Steroid. Jurnal Ilmiah Widya, 5 (3). pp. 1-5. ISSN 2338 3321

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Abstract

Sindrom Nefrotik Resisten Steroid (SNRS) adalah Sindrom Nefrotik yang gagal mencapai remisi setelah pemberian kortikosteroid dosis penuh dan alternatif. Penetapan remisi dilakukan dengan monitoring kadar protein dalam urin. Adanya proteinuria persisten dalam tiga kali pemeriksaan selama satu minggu menunjukkan bahwa pasien gagal mencapai remisi. Seorang anak lakilaki, usia 2 tahun dengan gejala edema anasarka, proteinuria masif, hipoalbuminemia, dan hiperlipidemia sesuai untuk Sindrom Nefrotik. Pasien sudah mendapat terapi prednison dosis penuh dan alternatif. Hasil urinalisis menunjukkan pasien mengalami proteinuria persisten sehingga didiagnosis sebagai Sindrom Nefrotik Resisten Steroid. Tujuan dari tulisan ini adalah menambah pengetahuan tentang Sindrom Nefrotik dan dapat mencegah terjadinya Sindrom Nefrotik Resisten Steroid (SNRS) dan komplikasi selanjutnya. Metode yang digunakan adalah studi kepustakaan dengan pendekatan deskriptif eksploratif dengan studi kasus dan penelusuran pustaka yang bersifat objektif, analitis, dan sistematis. Dapat disimpulkan bahwa pemeriksaan proteinuria penting untuk mengetahui terjadinya remisi pada pasien SN juga penting untuk mengetahui keberhasilan terapi SNRS dan memprediksi progresifitas menjadi gagal ginjal terminal. Kata kunci: Sindrom Nefrotik, Sindrom Nefrotik Resisten Steroid (SNRS), remisi, proteinuria. Steroid Resistant Nephrotic Syndrome (SNRS) is a Nephrotic Syndrome that fails to achieve remission after full and alternative doses of corticosteroids. Determination of remission is done by monitoring levels of protein in the urine. The presence of persistent proteinuria in three examinations for one week showed that the patient failed to achieve remission. A boy, 2 years old with symptoms of anarchic edema, massive proteinuria, hypoalbuminemia, and hyperlipidemia suitable for Nephrotic Syndrome. Patients have received fulldose and alternative prednisone therapy. The urinalysis results showed that the patient had persistent proteinuria and thus was diagnosed as a SteroidResistant Nephrotic Syndrome. The purpose of this paper is to increase knowledge about Nephrotic Syndrome and to prevent the occurrence of SteroidResistant Nephrotic Syndrome (SNRS) and subsequent complications. The method used is library research with an explorative descriptive approach with case studies and literature that are objective, analytical, and systematic. It can be concluded that proteinuria examination is important to find out the occurrence of remission in SN patients is also important to determine the success of SNRS therapy and predict progression to terminal renal failure. Keywords: Nephrotic Syndrome, Steroid Resistant Nephrotic Syndrome (SNRS), remission, proteinuria.

Item Type: Article
Subjects: MEDICINE
MEDICINE > Therapeutics. Pharmacology > Nonprescription drugs. Patent medicines
Depositing User: Ms Sari Mentari Simanjuntak
Date Deposited: 15 May 2020 03:18
Last Modified: 01 Jun 2020 17:50
URI: http://repository.uki.ac.id/id/eprint/1690

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