Hubungan Faktor Risko Terhadap Kejadian Stroke Pada Penderita Corona Virus Diseases-2019

Utomo, Tranggono Yudo (2022) Hubungan Faktor Risko Terhadap Kejadian Stroke Pada Penderita Corona Virus Diseases-2019. Syntax Literate: Jurnal Ilmiah Indonesia, 7 (4). pp. 3841-3850. ISSN 2548 1398

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Abstract

Stroke merupakan penyakit dengan mortalitas tertinggi kedua di dunia dan selama pandemi COVID-19 terjadi peningkatan kasus. Peningkatan ini terjadi akibat kekhawatiran mengakses fasilitas kesehatan disertai kondisi hiperinflamasi dan hiperkoagulasi pada pasien COVID-19. Penelitian ini menggunakan metode cross sectional. Sumber data berasal dari pasien terdiagnosis COVID-19 dengan SNH dan SH pada periode 26 Januari 2022 – 28 Februari 2022 RSUD dr. Chasbullah Abdulmadjid, Kota Bekasi, Jawa Barat. Faktor risiko yang ditinjau dalam penelitian ini adalah hipertensi, diabetes melitus, hiperkoagulasi, dislipidemia, merokok, dan CKD. Metode pengambila sampel menggunakan total sampling. Uji statistik menggunakan uji Fischer Exact.Sampel yang digunakan sebesar 36. Penderita SNH sebesar 91,7% dan SH sebesar 3,8%. Kelompok terbesar adalah pasien pria dengan SNH sebesar 100%, pasien usia 61-70 tahun dengan SNH sebesar 86,7%, dan pasien meninggal dengan SNH sebesar 100%. Tekanan darah didapatkan sebesar 157,78±16,58/87,78±10,72 mmHg, D-dimer sebesar 3,48±3,37 μl/ mL, ureum sebesar 82,36±85,9 mg/dL, dan kreatinin sebesar 2,31±3,68 mg/dL. Uji statistik menggunakan uji Fischer Exact didapatkan hubungan antara dislipidemia dengan terjadinya stroke pada penderita COVID-19 (p=0,04;p<0,05).Penelitian ini menunjukkan adanya hubungan antara dislipidemia dengan terjadinya stroke pada penderita COVID-19. Faktor risiko lainnya tidak memiliki hubungan akibat keadaan lain selama perawatan seperti sepsis, ARDS, hingga kegagalan multi organ. Kata kunci: COVID-19, Dislipidemia, Hiperinflamasi, SH, SNH / Stroke is the second highest mortality rate in the world and during COVID-19 pandemic there was an increase in cases. This occurs as result of worried to access health facilities and hyperinflammation and hypercoagulation in COVID-19 patients.This study used cross sectional. The data source comes from patients diagnosed with COVID-19 with SNH and SH in the period 26 January 2022 – 28 February 2022 RSUD dr. Chasbullah Abdulmadjid, Bekasi City, West Java. Risk factors reviewed in this study were hypertension, diabetes mellitus, hypercoagulation, dyslipidemia, smoking, and CKD. The sampling method used was total sampling. Statistical test using Fischer Exact test. The sample used was 36. Patients with SNH were 91.7% and SH were 3.8%. The largest groups were male patients with SNH at 100%, patients aged 61-70 years with SNH at 86.7%, and patients who died with SNH of 100%. Blood pressure obtained was 157.78±16.58/87.78±10.72 mmHg, D-dimer was 3.48±3.37 l/mL, urea was 82.36±85.9 mg/dL, and creatinine was 2.31±3.68 mg/dL. Statistical tests using the Fischer Exact test found relationship between dyslipidemia and the occurrence of stroke in patients with COVID-19 (p=0.04; p<0.05).This study showed significant relationship between dyslipidemia and the occurrence of stroke in patients with COVID-19. Other risk factors had no relationship due to other conditions during treatment such as sepsis, ARDS, to multi-organ failure. Keywords: COVID-19, Dyslipidemia, Hyperinflammation, SH, SNH

Item Type: Article
Subjects: MEDICINE
Depositing User: Ms Mentari Simanjuntak
Date Deposited: 19 Apr 2022 02:23
Last Modified: 19 Apr 2022 02:23
URI: http://repository.uki.ac.id/id/eprint/7676

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