Hubungan antara Tatalaksana Obat-Obatan Hipertensi pada Fase Akut terhadap Outcome Stroke Iskemik di Rumah Sakit Umum Universitas Kristen Indonesia pada periode 2019-2020

Senobua, Irasandi Marindatu (2021) Hubungan antara Tatalaksana Obat-Obatan Hipertensi pada Fase Akut terhadap Outcome Stroke Iskemik di Rumah Sakit Umum Universitas Kristen Indonesia pada periode 2019-2020. S1 thesis, Universitas Kristen Indonesia.

	Text (Hal_Judul_Abstrak_Daftar_Isi_Daftar_Gambar_Daftar_Tabel_Daftar_Lampiran) HalJudulAbstrakDaftarisi DaftarGambarDaftarTabel Daftarlampiran.pdf Available under License Creative Commons Attribution Non-commercial Share Alike. Download (1MB)
	Text (Bab_I) BABI.pdf Available under License Creative Commons Attribution Non-commercial Share Alike. Download (206kB)
	Text (Bab_II) BABII.pdf Restricted to Registered users only Available under License Creative Commons Attribution Non-commercial Share Alike. Download (802kB)
	Text (Bab_III) BABIII.pdf Restricted to Registered users only Available under License Creative Commons Attribution Non-commercial Share Alike. Download (248kB)
	Text (Bab_IV) BABIV.pdf Restricted to Registered users only Available under License Creative Commons Attribution Non-commercial Share Alike. Download (513kB)
	Text (Bab_V) BABV.pdf Restricted to Registered users only Available under License Creative Commons Attribution Non-commercial Share Alike. Download (195kB)
	Text (Daftar_Pustaka) DaftarPustaka.pdf Available under License Creative Commons Attribution Non-commercial Share Alike. Download (334kB)
	Text (Lampiran) Lampiran.pdf Restricted to Repository staff only Available under License Creative Commons Attribution Non-commercial Share Alike. Download (1MB)

Abstract

Stroke merupakan penyebab kematian utama di Indonesia dan tekanan darah tinggi sebagai faktor risiko utamanya. Obat hipertensi dapat menurunkan tekanan darah dan penelitian ini bertujuan untuk mengevaluasi hubungan antara tatalaksana obat hipertensi pada pasien stroke iskemik fase akut dengan outcome. Penelitian dilakukan secara restrospektif pada pasien stroke iskemik yang dirawat di Rumah Sakit Umum Universitas Kristen Indonesia tahun 2019-2020. Tekanan darah dikelompokkan berdasarkan joint national committee 7, kualitas hidup dinilai dengan The Stroke Specific Quality of Life Scale, dan diuji dengan Chi Square dan Man-Whitney test. Dari 105 pasien didapatkan laki-laki sebesar 53,3 % dan rentang usia 61-70 tahun sebanyak 39 (37,1%) orang. Sebanyak 47 (44,8%) pasien memiliki berat badan 61- 70 kg, dan didapatkan hubungan antara berat badan dengan tekanan darah, p < 0,05. Umumnya tekanan darah saat masuk berada pada kelompok prehipertensi yaitu 41 (39%) orang, bertambah jadi 50 (47,6%) orang saat keluar karena penurunan tekanan darah kelompok hipertensi I dan II. Tekanan darah rata-rata saat masuk adalah 141,78 mmHg dan saat keluar 135,47 mmHg, serta didapatkan perbedaan yang bermakna, p <0,05. Sebanyak 69 (65,7%) pasien mengkonsumsi amlodipin dan sisanya candesartan, rimipril, captopril dan furosemid. Ada perbedaan antara tekanan darah pasien yang mengkonsumsi amlodipin saat masuk dengan saat keluar, p <0,05%. Kualitas hidup 73 (69,5%) pasien adalah sedang, dan sisanya termasuk baik, serta tidak ada pasien dengan kualitas buruk. Hubungan antara obat hipertensi dengan outcome hanya berdampak pada kelompok hipertensi II yaitu p < 0,05. Penelitian ini membuktikan obat hipertensi berkorelasi positif dengan outcome pasien kelompok hipertensi II./Stroke is the leading cause of death in Indonesia and high blood pressure is the main risk factor. Hypertension drugs can lower blood pressure and this study aims to determine the relationship between hypertension drug management in acute phase ischemic stroke patients and outcomes. The study was conducted retrospectively on ischemic stroke patients who were treated at the Indonesian Christian University General Hospital in 2019-2020. blood pressure based on joint national committee 7, quality of life was assessed by The Stroke Specific Quality of Life Scale, tested by Chi Square and Man-Whitney test. From the 105 patients, 53.3% were male and 39 (37.1%) aged 61-70 years old. A total of 47 (44.8%) patients weighed 61-70 kg, and found a relationship between body weight and blood pressure, p < 0.05. Generally, blood pressure at admission was in the prehypertension group, are 41 (39%) people, increased to 50 (47.6%) people when they left because of the decrease in blood pressure in hypertension groups I and II. The average blood pressure at admission was 141.78 mmHg and at exit was 135.47 mmHg, and there was a significant difference, p <0.05. A total of 69 (65.7%) patients took amlodipine and the rest of candesartan, rimipril, captopril and furosemide. There was a difference between the blood pressure of patients taking amlodipine at admission and discharge, p < 0.05%. Quality of life for 73 (69.5%) patients was moderate, including good, and there were no patients with poor quality. The relationship between hypertension drug and outcome only had an impact on hypertension group II, there are p < 0.05. This study proves that hypertension drugs are positively correlated with the results of patients in the hypertension group II.

Actions (login required)

View Item