CHRONIC INFLAMMATORY DEMYELINATING POLYRADICULOPATHY

Tobing, Noer Hassianni Mercy L. and Wijaya, Agus Yudha and Aritonang, Christina and Bijaksono, Yoyok Hendro (2021) CHRONIC INFLAMMATORY DEMYELINATING POLYRADICULOPATHY. Jurnal Kedokteran, 9 (1). pp. 1257-1264. ISSN 2723 5890

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Abstract

Chornic inflammatory demyelinating polyradiculoneuropathy (CIDP) merupakan penyakit immune-mediated neuropati (neuropati karena gangguan imunologis), penyakit yang jarang, langka dan bentuknya bermacam-macam (heterogen), tetapi dapat diobati. Selama abad 20 pengenalan CIDP masih terbatas, sehingga sebutan nama penyakit berbeda-beda. Deskripsi klinis dan histopatologis sering bercampur dengan penyakit mirip seperti sindrom Guillain-Barre’. Untuk mendiagnosis penyakit CIDP perlu dilakukan pemeriksaan eletromiografi (EMG) menilai kecepatan hantar saraf dan merupakan pemeriksaan diagnostik pasti. Ultrasound saraf dan MRI dapat pula membantu dalam diagnosis. CIDP terbagi dalam dua tipe yaitu tipikal CIDP dan varian atipikal CIDP. Varian atipikal CIDP dengan fenotipen berbeda menjadi tantangan dalam melakukan diagnosis. Kata kunci : CIDP, Gangguan Imune Mediate yang didapat, Jarang, Kasus sulit, Terapi jamgka panjang/Chornic inflammatory demyelinating polyradiculoneuropathy (CIDP) it is an disease of immune-mediated neuropathy (neuropathy due to immunological disorders), rare, the disease that can take many forms (heterogeneous), but treatable,. For much of 20th centuries the introduction of CIDP has been limited so that it is referred to under different disease names. Clinical and histopathologic descriptions are often confused with a disease-like appearance such as Guillain-Barre 'syndrome. To diagnose CIDP, it is necessary to perform an eletromyography (EMG) examination to assess the velocity of nerve conduction and this is an definite diagnostic test. Neural ultrasound and MRI can also help in diagnosis. CIDP is divided into two types, namely typical CIDP and atypical variants of CIDP. Atypical variants of CIDP with different phenotypes present a diagnostic challenge. Keywords : CIDP, Acquired Imune mediated disorder, Rare case, Difficulty case, Longterm treatment

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