Gambaran Efektivitas Seftriakson Dan Sefotaksim Pada Pasien Demam Tifoid Usia 5 – 19 Tahun Di RSUD Bekasi Periode Januari 2019 - Desember 2019

Marvellini, Richard Yan and Sagala, Fenesa Tesalonika Bunga Ria (2020) Gambaran Efektivitas Seftriakson Dan Sefotaksim Pada Pasien Demam Tifoid Usia 5 – 19 Tahun Di RSUD Bekasi Periode Januari 2019 - Desember 2019. JURNAL KEDOKTERAN UNIVERSITAS PALANGKA RAYA, 8 (2). pp. 1020-1024. ISSN 2723 5890

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Abstract

Typhoid fever is an intestinal infection caused by the bacterium Salmonella Typhi. However, this disease is still a health problem in Indonesia due to its high incidence. This disease’s transmission is related to the clean and healthy lifestyle behavior of each individual. Treatment for the typhoid fever is antibiotic and resistance has been found in its first line, chloramphenicol. For the second line ,ceftriaxone and cefotaxime, has become the choice as a substitute for the first line. This is associated with good effectiveness in treating typhoid fever patients. The research using content analysis method which is analyzed descriptively and retrospectively using medical records from RSUD on January 2019 - December 2019 period as the secondary data. Based on the results of research regarding heat-free time and length of treatment, it was found that the ceftriaxone and cefotaxime antibiotics were effective in treating typhoid fever. The Mann Whitney U correlation test performed in this research and obtained a coefficient of p 0.06 and p 0.063 (p> 0.05), which means that it can be concluded that there is no significant difference between the use of ceftriaxone and cefotaxime antibiotics. The conclusion that can be drawn from this study is ceftriaxone and cefotaxime are the effective antibiotics in treating typhoid fever. Keywords : Typhoid Fever, Salmonella Typhi, ceftriaxone, cefotaxime

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