The effect of selenium and multiple micronutrient administration during periconception periodon the level of malondialdehyde

Monoarfa, Yustiyanty and Gumilar, Erry and Widasari, Lucy and Yekti, Rahayu and Otoluwa, Anang S. and Thaha, Abd. Razak (2020) The effect of selenium and multiple micronutrient administration during periconception periodon the level of malondialdehyde. Enfermeria Clinica, 30. pp. 114-118.

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Abstract

MalondialdehydeAbstractObjective: This study aimed to prove the effect of Selenium during periconception to the levelof Malodialdehyde in pregnancy.Methods: This study was double blind, randomised, control community based trial design. Theintervention group (10 periconception women) received Selenium in Multimicronutrient (MMN),while the control group (22 periconception women) given capsules containing Iron and FolicAcid. During preconceptional period, the capsules was given once a week, while in pregnantwomen was once a day. At the 12th and 20th weeks of pregnancy, selenium and MDA weremeasured. Statistical analysis using independent T-test, Paired T-Test and PLS analysis.Results: At the 12th weeks of pregnancy the level of MDA in Multimicronutrient group was121.2 ng/mL and IFA group was 1436 ng/mL, and at the 20th weeks in MMN group was 108.4 ng/Mland IFA group was 199.6 ng/mL. There was a no significant difference between MDA in twogroups (p = 0.424) at 12th week, but at 20th weeks MMN group had a significantly lower MDAlevels (p = 0.006) than IFA group.Conclusion: The administration of selenium in MMN preparations since the preconception periodhas

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