Ferritin sebagai marker defisiensi besi

Luhulima, Danny Ernest Jonas (2024) Ferritin sebagai marker defisiensi besi. In: Prosiding Seminar Nasional : Stunting : Education Perspective. UKI Press, Jakarta, pp. 117-120. ISBN 978 623 8287 30 7

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Abstract

Stunting (WHO) is a nutritional disorder in children based on body length or height that is less than the age of their peers (> -2SD). Diagnosing stunting is quite simple, but our job is to prevent stunting from occurring. Clinical and laboratory data can be used to predict the risk of stunting. The stunting examination laboratory consists of basic examinations: complete blood count, urinalysis, and routine stool. Routine metabolic screening includes random blood glucose, blood gas analysis, lactate, ammonia, ketone bodies, amino acid profiles, and urine organic acids, while additional examinations include culture, iron profile, electrolytes, kidney function, liver function, thyroid hormones, infection exploration, and IgE. Of the many tests, one that can assess the risk of stunting due to iron deficiency is ferritin. Hemoglobin is sensitive for iron deficiency anemia but not for iron deficiency. Iron deficiency can be severe even if the Hb is normal, so the clinician will be late in the diagnosis if they rely on the Hb.Keywords: stunting, iron deficiency, ferritin / Stunting (WHO) adalah kelainan gizi pada anak berdasarkan panjang/tinggi badan kurang dibandingkan umur anak sebayanya (> -2SD). Mendiagnosis stanting cukup sederhana, namun tugas kita adalah mencegah terjadinya stunting. Klinis dan laboratorium dapat digunakan untuk memprediksi resiko stunting. Laboratorium pemeriksaan stunting terdiri dari pemeriksaan dasar: darah lengkap, urinalisis dan feses rutin. Skrining rutin metabolik antara lain glukosa darah sewaktu, analisis gas darah, laktat, ammonia, benda keton, profil asam amino dan asam organik urin, sedangkan pemeriksaan tambahan seperti kultur, profil besi, elektrolit, fungsi ginjal, fungsi hati, hormon tiroid, eksplorasi infeksi, IgE. Dari sekian banyak pemeriksaan salah satu pemeriksaan yang dapat menilai resiko stunting akibat defisiensi besi adalah ferritin. Hemoglobin sensitif untuk anemia defisiensi besi tetapi tidak untuk defisiensi besi. Defisiensi besi bisa parah meskipun Hb normal, sehingga klinisi akan terlambat diagnosis jika berpegangan pada Hb. Kata kunci Stunting, defisiensi besi, ferritin

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