Monitoring Viral Load RNA And Cd4+ Count on HIV Patients Receiving ARV Therapy

Luhulima, Danny Ernest Jonas and Simanjuntak, Tiroy Sari B. and Simanjuntak, Christine Debora Aprilia and Amelia, Ria (2025) Monitoring Viral Load RNA And Cd4+ Count on HIV Patients Receiving ARV Therapy. International Journal of TROPICAL DISEASE & Health, 46 (3). pp. 56-64. ISSN 2278 1005

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Abstract

Human Immunodeficiency Virus (HIV) is a virus that threatens the quality of human life. HIV is a retrovirus that uses RNA as its genome so this virus can replicate very well. HIV will cause persistent disease so HIV-confirmed patients must be taking medication for life. HIV patients need to receive therapy and monitor Viral Load RNA and CD4+ count levels. Generally, routine checks are carried out every 3-6 months. Viral Load RNA levels show how much virus is in the blood while CD4+ count represents patient immunity. Normally Viral Load RNA and CD4+ count will show the same results inversely proportional. The higher the Viral Load RNA and the lower the CD4+ count, the more the patient's condition will get worse, and vice versa. Papua is one of the provinces in Indonesia with the highest HIV rate with faster spread compared to other provinces. To overcome this problem, the government has provided free therapy for the Indonesian people. This therapy called antiretroviral can be obtained free of charge and must be taken by people all patients are HIV positive Aims: To determine Viral Load RNA levels and CD4+ count in HIV patients treated with ARV at Abepura District Hospital. Place and Duration of Study: The research was carried out in the VCT medical records section of Abepura Regional Hospital from August 2023 to November 2023. Methodology: This type of research is descriptive-analytical research with a design cross-sectional retrospective study using secondary data in the form of Abepura Regional Hospital medical records. The population in this study was treated HIV-positive patients ARVs at Abepura Regional Hospital from 2019 to 2022. This research uses a total sampling method. The research sample in this study were medical records of patients who were positive for HIV/AIDS and had been treated with ARVs at Abepura Regional Hospital from 2019 to 2022 Results: The results were obtained with more diverse patient characteristics female (52.9%), aged 25—49 years (68.6%), and heterosexual (81.4%). Overall the therapy showed success with an increase in undetected RNA patients were 24% and an increase in patients with normal CD4+ count of as much as 76% during three years of monitoring. The success of this therapy can occur if there is compliance in taking medication from the patient, there is good cooperation between staff health and patients, as well as support from the patient environment. Conclusion: Data collection for this research will start from August 2023 until September 2023 and be obtained from hospital medical records Abepura Regional General. In this study, patients who were HIV positive and 85 people received ARV therapy at Abepura District Hospital There were 70 research samples that met the routine inclusion criteria control every 6 months. Keywords: HIV; viral load; RNA; CD4+; ARV; ART

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