Mixed Ovarian Carcinoma Comprising Clear Cell Carcinoma and Endometrioid Carcinoma: A Case Report

Susanto, Jason D. and Nelwan, Praisela S. Hendrieta and Gultom, Fajar Lamhot and Sirait, Batara I. and Effendi, Iwan K (2024) Mixed Ovarian Carcinoma Comprising Clear Cell Carcinoma and Endometrioid Carcinoma: A Case Report. Cureus, 16 (11). pp. 1-9.

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Abstract

We present a unique case of mixed ovarian carcinoma, including both clear cell carcinoma (CCC) and grade 1 endometrioid carcinoma (EC) in a 49-year-old woman. The patient had no complaints of pain but presented with an enlarged abdomen, necessitating a thorough diagnostic assessment. Histopathological evaluation revealed an unusual histological juxtaposition of CCC coexisting with grade 1 EC found in an ovarian mass, resulting in diagnostic and therapeutic challenges. A comprehensive approach was used to treat this particular case of mixed ovarian cancer, which included surgical procedures and adjuvant treatments. This case emphasizes the significance of identifying and assessing mixed ovarian carcinomas in order to develop customized treatment plans, as well as the necessity of further research into the basic underlying causes of such unusual presentations. Categories: Obstetrics/Gynecology, Pathology, Oncology Keywords: epithelial ovarian cancer, mixed ovarian carcinoma, ovarian cancers, ovarian clear cell carcinoma, ovarian endometrioid adenocarcinoma

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