Korelasi antara Sindrom Klinis Covid-19 dengan Systemic Inflammatory Response Syndrome (SIRS)

Wahyuningsih, Tri (2021) Korelasi antara Sindrom Klinis Covid-19 dengan Systemic Inflammatory Response Syndrome (SIRS). S1 thesis, Universitas Kristen Indonesia.

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Abstract

Covid-19 yang telah dikonfirmasi dilaporkan secara global sebanyak 83.015.212 kasus pada 31 Desember 2020. Kemudian, sindrom klinis yang didapat pada kasus Covid-19 tidak memiliki gejala yang spesifik. Penelitian ini bertujuan untuk mengetahui sindrom klinis Covid-19 dengan SIRS berdasarkan kriteria konsensus konferensi ACCP/SCCM 1991, yaitu terdapat 2-4 gejala dari temperatur >38oC atau <36oC, frekuensi nadi >90x/menit, frekuensi napas >20x/menit atau PaCO2<32 mmHg, dan jumlah leukosit >12.000 sel/µL atau <4000 sel/µL. Penelitian ini dilakukan dengan desain deskriptif analisis regresi linier bivariat dengan menggunakan pendekatan crossectional, diperoleh 41 sampel pasien yang terkonfirmasi Covid-19 di salah satu Rumah Sakit Swasta di Bekasi Timur yang dilakukan pada bulan Juni ̶ November 2020. Penelitian ini menunjukkan korelasi yang signifikan secara statistik antara sindrom klinis Covid-19 dengan SIRS (P = 0,000) dengan uji korelasi Spearman. Kata Kunci : Covid-19, SIRS, PCR. / Covid-19 has been confirmed reported globally as many as 83.015.212 cases on December 31, 2020. Then, the clinical syndrome acquired in Covid-19 cases has no specific symptoms. This research aims to know the description and correlation between the clinical syndrome of Covid-19 with SIRS based on the 1991 ACCP / SCCM conference consensus criteria, there were 2-4 symptoms from temperature >38oC or <36oC, heart rate >90x/minute, respiration rate> 20x/minute or PaCO2<32 mmHg, and leukocyte count >12,000 cells / µL or <4000 cells / µL. The study design used cross-sectional by descriptive of bivariate linear regression analysis, 41 samples of patients had been comfirmed Covid-19 were obtained at a private hospital in East Bekasi in June ̶ November 2020. This study showed a statistically significant correlation between the clinical syndrome of Covid-19 and the SIRS (P = 0.000) tested with Spearman’s correlation test. Keywords: Covid-19, SIRS, PCR

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