Testing the Effectiveness of Mangosized Skin Extract (Garcinia mangostana) as an Antimicrobial Against Bacteria Causing GI Tract Infections

Pohan, Dame Joyce and Fatimazahra, Adinda Octarizqika and Ronny, Ronny (2024) Testing the Effectiveness of Mangosized Skin Extract (Garcinia mangostana) as an Antimicrobial Against Bacteria Causing GI Tract Infections. Galore International Journal of Health Sciences and Research, 9 (3). pp. 7-14. ISSN 2456-9321

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Abstract

The mangosteen fruit, which in Latin is called Garcinia mangostana Linn, is a plant whose entire parts can be used, including the skin of the fruit. Mangosteen fruit has bioactive compounds such as xanthones, especially α, β, and γ-mangostin where the level of antimicrobial action of αmangosteen has been explored by many researchers and it has been observed that it is not only effective against bacteria but also against other microbes such as fungi and mycobacteria. Gastrointestinal system infections are a serious health problem and have not been completely resolved until now because cases are increasing every year. Gastrointestinal tract infections are a health problem in the world, including in Indonesia. Some infectious diseases of the gastrointestinal system that are often found in the wider community are typhoid fever, paratyphoid fever, diarrhea, and gastroenteritis. The bacteria that cause typhoid fever and paratyphoid fever are caused by the bacteria Salmonella Typhi & Salmonella Paratyphi. While diarrhea and gastroenteritis are caused by food poisoning and drinks contaminated by E. coli. This research is an experimental laboratory research using the disc diffusion/Kirby Bauer method by measuring the diameter of the clear zone which is a sign that there is an obstacle to the growth of Salmonella typhi and E. Coli bacteria by the antimicrobial compounds contained in the mangosteen fruit extract. The calculation results of this research showed that mangosteen peel extract (Garcinia Mangostana L) against E. Coli bacteria with the antibiotic Chloramphenicol as control showed an average diameter of the inhibition zone of 30.5 mm, whereas Salmonella bacteria were not found or no inhibition zone was formed at the smallest concentration up to greatest concentration Keywords: Mangosteen Peel, garcinia mangostana l., Gastrointestinal Infections, Effectiveness of Mangosteen Peel, Antibiotics

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