Behaviour test in chronic brain ischemia rats: A bibliometric approach

Susantiningsih, Tiwuk and Makkiyah, Feda and Thadeus, Maria Selvester and Rizkianti, Tuty and Muktamiroh, Hikmah and Amalia, Muttia and Setyaningsih, Yuni and Citrawati, Mila and Fauziah, Cut and Bahar, Meiskha and Chairani, Aulia and Harjono, Yanti and Irmarahayu, Agneta and Wahyuningsih, Sri and Zulfa, Fajriati (2022) Behaviour test in chronic brain ischemia rats: A bibliometric approach. F1000Research. pp. 1-13.

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Background: Stroke causes severe disability and mortality. Despite the fact that the pathology of acute stroke is well understood, publication on chronic stroke is still limited. Because scarring of glia limits the recovery area of acute stroke and reorganization capacity is reduced, discovering new treatments for chronic stroke poses substantial obstacles. In stroke research, rodent models are commonly utilized, and behavior testing is a crucial tool. To measure stroke outcomes and translating rodent findings to therapeutic trials, selecting relevant behavioral tests that fit the study purpose is critical. Here, we aimed to look at the last decade’s publications highlighting behaviour tests on chronic stroke rats. Hopefully, we were able to give more information about the behaviour tests to facilitate the researchers’ choice of appropriate test. Methods: By using a bibliometric analysis, we hope to systematically discuss rodent behavior tests in chronic stroke research. Documents were extracted from the Scopus database in April 2022. Excel and VOSviewer 1.6.18 were used to conduct statistical and graphical analysis. Results: Research on "behavioral test in chronic stroke rats" has progressed quickly, although the researchers have yet to collaborate with each other. H. Millani was an active researcher and author who connected numerous researchers, according to documents and citation analysis. “Animals”, “brain ischemia”, “man”, “publication”, and “animal experiment” were all common keywords. The majority of the articles were from the United States and China. The Morris Water Maze test and the cylinder test were the most commonly used behavior tests Conclusions Clinical applications and therapeutic effectiveness against stroke could be improved with more collaboration amongst authors. When using a behavior test, researchers need to think about which neurological deficiency is being addressed and whether the test covers long-term evaluation. Keywords Bibliometric analysis, Scopus, Stroke, chronic, behaviour test, rats

Item Type: Article
Subjects: MEDICINE
Depositing User: Mr Sahat Maruli Tua Sinaga
Date Deposited: 23 May 2023 07:18
Last Modified: 23 May 2023 07:18

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